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1. Introduction 2. Overview of CRISPR-Cas Systems 2.1 Historical background 2.2 Mechanism of action 2.3 Types and classifications 3. Antimicrobial Resistance 3.1 Definition and importance 3.2 Current global impact 3.3 Mechanisms of resistance 4. CRISPR-Cas Systems and Bacterial Immunity 4.1 Adaptive immune mechanisms 4.2 Genome editing capabilities 4.3 Interaction with phages 5. Role of CRISPR-Cas in Antimicrobial Resistance 5.1 Gene regulation effects 5.2 Impact on horizontal gene transfer 5.3 Potential modification of resistance genes 6. Biochemical Analysis of CRISPR Function 6.1 Molecular structure and composition 6.2 Enzymatic activities 6.3 Techniques for studying CRISPR 7. Implications for Antimicrobial Therapy 7.1 Novel therapeutic strategies 7.2 Challenges and limitations 7.3 Future perspectives 8. Conclusion and Future Outlook 8.1 Summary of key findings 8.2 Potential for future research 8.3 Impact on public health policies
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