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1. Introduction 2. Background of CRISPR-Cas9 2.1 History and Development 2.2 Mechanism of Action 2.3 Comparison with other Gene Editing Tools 3. Current Applications in Agriculture 3.1 Crop Yield Improvement 3.2 Pest and Disease Resistance 3.3 Climate Adaptation Strategies 4. Potential Innovations for Sustainability 4.1 Resource Efficiency Enhancement 4.2 Reducing Environmental Impact 4.3 Soil Health and Biodiversity 5. Ethical Considerations 5.1 Public Perception and Acceptance 5.2 Regulatory Challenges 5.3 Intellectual Property Issues 6. Case Studies 6.1 Successful Implementations 6.2 Lessons Learned from Failures 6.3 Regional Variations in Application 7. Challenges and Limitations 7.1 Technical Barriers 7.2 Economic Constraints 7.3 Socio-political Hurdles 8. Future Prospects 8.1 Emerging Technologies Integration 8.2 Long-term Impact Projections 8.3 Pathways for Policy Development
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