Az 1-es típusú diabétesz és az inzulinkezelés hatása az enterális idegrendszer neuron/gliasejt arányára patkány myentericus ganglionokban

1. Introduction 2. Type 1 Diabetes Mellitus Overview 2.1. Pathophysiology of Type 1 Diabetes 2.2. Diagnostic Criteria and Epidemiology 2.3. Current Treatment Strategies 3. Insulin Treatment in Diabetes 3.1. Mechanism of Insulin Action 3.2. Insulin Therapy Protocols 3.3. Challenges and Complications 4. Enteric Nervous System Structure 4.1. Anatomy and Function 4.2. Myenteric Ganglia Characteristics 4.3. Neuron and Glial Cell Types 5. Neuron/Glia Ratio in Myenteric Ganglia 5.1. Importance of Neuron/Glia Balance 5.2. Methods to Assess Ratio 5.3. Variability Across Species 6. Impact of Diabetes on Enteric System 6.1. Alterations Due to Hyperglycemia 6.2. Experimental Findings in Model Organisms 6.3. Long-term Consequences 7. Effect of Insulin on Neuron/Glia Ratio 7.1. Influence of Insulin on Neuronal Health 7.2. Glial Response to Insulin Treatment 7.3. Comparative Studies in Rats 8. Research Methodology 8.1. Animal Model and Experimental Design 8.2. Techniques for Neuron/Glia Assessment 8.3. Statistical Analysis Procedures 9. Conclusion and Future Directions 9.1. Summary of Key Findings 9.2. Implications for Diabetes Management 9.3. Recommendations for Further Research