A Systematic Review of Chronic Glyphosate Exposure and its Potential Link to Cancer Development

1. Introduction 1.1 Background and Rationale 1.2 Objectives of the Review 1.3 Research Questions 2. Glyphosate: An Overview 2.1 Chemical Composition and Use 2.2 Mechanism of Action 2.3 Environmental and Health Concerns 3. Methodology 3.1 Literature Search Strategy 3.2 Inclusion and Exclusion Criteria 3.3 Data Extraction and Management 3.4 Quality Assessment of Studies 4. Results 4.1 Study Selection and Characteristics 4.2 Overview of Findings 4.3 Summary of Data Analysis 5. Chronic Glyphosate Exposure 5.1 Routes and Extent of Exposure 5.2 Bioaccumulation and Metabolism 5.3 Factors Influencing Exposure Levels 6. Cancer Development Mechanisms 6.1 Biological Pathways Affected 6.2 Genotoxic Effects 6.3 Carcinogenicity Evidence 7. Discussion 7.1 Interpretation of Results 7.2 Comparison with Existing Literature 7.3 Limitations of the Current Review 8. Conclusion 8.1 Summary of Key Findings 8.2 Implications for Public Health 8.3 Recommendations for Future Research